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Equitable Access Policy

Equitable Access Policy

The University of Maryland Equitable Access Policy provides equitable, open access to the University's research and scholarship. Faculty can learn more about what is covered by the policy and how to deposit on the policy website.
Theses and Dissertations

Theses and Dissertations

DRUM includes all UMD theses and dissertations from 2003 forward.

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Recent Submissions

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    BenefitsSpatialTraining
    (2026-09-23) Mix, Kelly S.; Levine, Susan C.
    This dataset is a modification of a previous dataset from the same study (Spatial Training and Math Outcomes Grades 1 and 6: http://hdl.handle.net/1903/25314) that was created to support a secondary data analysis project focused on individual differences in responses to training (Who Benefits from Spatial Training?). We are posting it separately to facilitate further analyses of this type. The specific modifications include (1) both grades are included in the same data file; (2) the modified file includes SES data; (3) the modified file includes mathematics composite scores at pretest and posttest (vs. only separate mathematics measures included in the original), and (4) the modified file includes the variables for initial mathematics skill and initial spatial skill. Some variables were also omitted in this version as they were not used in the individual differences analyses, such as child age (in both raw and recalculated formats), school codes, and data for children in the control group.
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    Electronic Supporting Data: Tetrachloroanthracene-Walled Glycoluril Trimer: Solvent-Dependent Conformational Switching and Host-Guest Binding
    (Royal Society of Chemistry, 2026) Arora, Niyati; Shaurya, Alok; Arcudia, Jessica; Merino, Gabriel; Isaacs, Lyle; Isaacs, Lyle
    We report the synthesis of a tetrachloroanthracene walled glycoluril trimer based host (H1) that adopts a time-averaged C2v-symmetric structure in DMSO but a self-satisfied “flipped-out” time-averaged Cs-symmetric structure in water. Dicationic guests like Me6PXDA form the cavity inclusion complexes Cs-H1•Me6PXDA and C2v-H1•Me6PXDA in water and DMSO, respectively.
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    Methodology Report for Greenhouse Gas Inventory and Analysis by U.S. State: 1990-2024
    (2026-09-17) Desai, Mausami; Camobreco, Vincent; Hedger, Toby; Irving, William; Rewcastle, Kenna; Steller, John; Barbieri, Lindsay; Weitz, Melissa; Murumkar, Tanvi; Patel, Anusha; Averyt, Mollie; Bronstein, Katherine; Butler, Jake; Chinery, Leslie; Edquist, Kara; Ferenchiak, Rebecca; Garfinkel, Johanna; Hakos, Matt; Icenhour, Melissa; Kaelin, Jeremy; Kerr, Emily; Long, Brandon; Manne, Gopi; Moore, Tiffany; Rabemiarisoa, Ajo; Randall, David; Robinson, Libby; Schaffner, Karen; Scully, Peter; Stonebrook, Sophia; Stout, Tara; Thompson, Emily; Vanek, Riley; Fawcett, Allen; Lou, Jiehong; Cui, Ryna; Hultman, Nate
    The Methodology Report for Greenhouse Gas Inventory and Analysis by U.S. State: 1990-2024 describes the methodologies used by the Center for Global Sustainability (CGS) to disaggregate national-level anthropogenic greenhouse gas (GHG) emissions and sinks to the state level while maintaining consistency with the Greenhouse Gas Inventory and Analysis for the United States: 1990-2024 (GHGIA) (Desai et al., 2026). CGS intends to continue publishing the national-level GHGIA annually each April, presenting time-series estimates by gas, source or sink, and sector. The complementary state-level estimates, hereafter referred to as the GHGIA by State, will be published annually following the release of the national-level report.
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    Purification and Functional Characterization of PlyN74 Endolysin for Antibacterial Applications
    (2026) Costello, Emily; Rodriguez, Nathalie; Gunasekara, Ravindu; O'Hara, Jessica
    Antibiotic resistance is a growing problem in the medical field, which requires the development of alternative medicines to treat patients with bacterial infections. Bacteriophage endolysin proteins such as N74 have been shown to target Bacillus cereus as well as Bacillus anthracis (anthrax). This study aims to characterize the effectiveness of N74 at facilitating lysis of Bacillus cereus and how lysis can be augmented through use of endolysins plyG and P56, in conjunction with N74. A recombinant version of the N74 protein with a 6x-HIS tag was overexpressed and purified from E. coli using sonication and Ni-NTA columns. We used a BCA assay to measure protein concentration. tested the activity of the protein by conducting spectrophotometric lysis assays and log-fold killing assays were used to characterize the lytic activity of N74 against B.cereus. Our results show that PlyN74 is indeed an effective protein to lyse B. cereus. The BCA assay was successful in showing that N74 was purified and the SDS-PAGE showed the proper band size in the gel. The log-fold killing assays showed a decrease in bacterial growth. Our results demonstrated the effectiveness of PlyN74 at lysing Bacillus cereus and characterized the effects of endolysins PlyG and P56 on lysis when used alongside PlyN74. While previous studies have shown that endolysins that lyse Bacillus cereus have been able to lyse Bacillus anthracis, further testing is required to determine the effectiveness of PlyN74 on Bacillus anthracis. The results will ultimately aid in the discovery of new alternatives to antibiotics.