Genome changes due to artificial selection in U.S. Holstein cattle

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Ma, L., Sonstegard, T.S., Cole, J.B. et al. Genome changes due to artificial selection in U.S. Holstein cattle. BMC Genomics 20, 128 (2019).

Abstract

The availability of a unique unselected Holstein line since 1964 provided a direct comparison between selected and unselected Holstein genomes whereas large Holstein samples provided unprecedented statistical power for identifying high-confidence SNP effects. Utilizing these unique resources, we aimed to identify genome changes affected by selection since 1964.

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