Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations
dc.contributor.author | Fang, Lingzhao | |
dc.contributor.author | Liu, Shuli | |
dc.contributor.author | Liu, Mei | |
dc.contributor.author | Kang, Xiaolong | |
dc.contributor.author | Lin, Shudai | |
dc.contributor.author | Li, Bingjie | |
dc.contributor.author | Connor, Erin E. | |
dc.contributor.author | Baldwin, Ransom L. VI | |
dc.contributor.author | Tenesa, Albert | |
dc.contributor.author | Ma, Li | |
dc.contributor.author | Liu, George E. | |
dc.contributor.author | Li, Cong-jun | |
dc.date.accessioned | 2021-06-07T16:03:45Z | |
dc.date.available | 2021-06-07T16:03:45Z | |
dc.date.issued | 2019-08-16 | |
dc.description.abstract | The functional annotation of genomes, including chromatin accessibility and modifications, is important for understanding and effectively utilizing the increased amount of genome sequences reported. However, while such annotation has been well explored in a diverse set of tissues and cell types in human and model organisms, relatively little data are available for livestock genomes, hindering our understanding of complex trait variation, domestication, and adaptive evolution. Here, we present the first complete global landscape of regulatory elements in cattle and explore the dynamics of chromatin states in rumen epithelial cells induced by the rumen developmental regulator—butyrate. | en_US |
dc.description.uri | https://doi.org/10.1186/s12915-019-0687-8 | |
dc.identifier | https://doi.org/10.13016/ao9b-qktf | |
dc.identifier.citation | Fang, L., Liu, S., Liu, M. et al. Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations. BMC Biol 17, 68 (2019). | en_US |
dc.identifier.uri | http://hdl.handle.net/1903/27119 | |
dc.language.iso | en_US | en_US |
dc.publisher | Springer Nature | en_US |
dc.relation.isAvailableAt | College of Agriculture & Natural Resources | en_us |
dc.relation.isAvailableAt | Animal & Avian Sciences | en_us |
dc.relation.isAvailableAt | Digital Repository at the University of Maryland | en_us |
dc.relation.isAvailableAt | University of Maryland (College Park, MD) | en_us |
dc.subject | Cattle genome | en_US |
dc.subject | Functional annotation | en_US |
dc.subject | Chromatin states | en_US |
dc.subject | Butyrate | en_US |
dc.subject | Rumen development | en_US |
dc.title | Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations | en_US |
dc.type | Article | en_US |
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