Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations

Simple item page
dc.contributor.authorFang, Lingzhao
dc.contributor.authorLiu, Shuli
dc.contributor.authorLiu, Mei
dc.contributor.authorKang, Xiaolong
dc.contributor.authorLin, Shudai
dc.contributor.authorLi, Bingjie
dc.contributor.authorConnor, Erin E.
dc.contributor.authorBaldwin, Ransom L. VI
dc.contributor.authorTenesa, Albert
dc.contributor.authorMa, Li
dc.contributor.authorLiu, George E.
dc.contributor.authorLi, Cong-jun
dc.date.accessioned2021-06-07T16:03:45Z
dc.date.available2021-06-07T16:03:45Z
dc.date.issued2019-08-16
dc.description.abstractThe functional annotation of genomes, including chromatin accessibility and modifications, is important for understanding and effectively utilizing the increased amount of genome sequences reported. However, while such annotation has been well explored in a diverse set of tissues and cell types in human and model organisms, relatively little data are available for livestock genomes, hindering our understanding of complex trait variation, domestication, and adaptive evolution. Here, we present the first complete global landscape of regulatory elements in cattle and explore the dynamics of chromatin states in rumen epithelial cells induced by the rumen developmental regulator—butyrate.en_US
dc.description.urihttps://doi.org/10.1186/s12915-019-0687-8
dc.identifierhttps://doi.org/10.13016/ao9b-qktf
dc.identifier.citationFang, L., Liu, S., Liu, M. et al. Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations. BMC Biol 17, 68 (2019).en_US
dc.identifier.urihttp://hdl.handle.net/1903/27119
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Agriculture & Natural Resourcesen_us
dc.relation.isAvailableAtAnimal & Avian Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectCattle genomeen_US
dc.subjectFunctional annotationen_US
dc.subjectChromatin statesen_US
dc.subjectButyrateen_US
dc.subjectRumen developmenten_US
dc.titleFunctional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variationsen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
s12915-019-0687-8.pdf
Size:
3.89 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.57 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Animal & Avian Sciences Research Works