EXERCISE AND PREVALENCE AND FIRST ONSET DEPRESSION IN WOMEN OF CHILDBEARING AGE

Abstract

Background: Major depressive disorder is the leading cause of disability disproportionately affecting women of reproductive age. Prior research suggests that exercise may be an effective preventative measure. Objective: To examine the association between exercise and current and first onset major depressive episodes (MDE) among women 20-45 years (n=8175) participating in National Epidemiologic Study of Alcohol and Related Conditions II (2004-2005). Methods: Logistic regression models were used to examine the relationship between exercise and MDE prevalence and incidence. Results: Some exercise was associated with elevated odds of first onset MDE, compared to no exercise, but this association was not significant after controlling for covariates (adjusted odds ratio = 0.87, 95% confidence interval:0.75-1.01). No other associations were observed. Conclusion: This study did not find evidence of an association between exercise and prevalence or incidence of MDE in reproductive-aged women. Future research with prospective study designs and objective exercise measures needed.