Determination of Network Connectivity: Algorithms and Applications in Organ Systems

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dc.contributor.advisorNewcomb, Robert Wen_US
dc.contributor.authorNiruntasukrat, Aimaschanaen_US
dc.contributor.departmentElectrical Engineeringen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2015-02-14T06:30:27Z
dc.date.available2015-02-14T06:30:27Z
dc.date.issued2011en_US
dc.description.abstractIn this dissertation, we develop methods to determine the existence and types of connections between network nodes when the available data are only states (or signals) of such nodes. The proposed method determines the types of connections by examining the nodes' interaction. Determination inaccuracy caused by different reactive time scales between nodes is addressed by using wavelet analysis. After the network signals are decomposed into signals at different scales, the most prominent scale of each signal is obtained through energy comparison, and then is utilized to calculate connectivity indices which determine the existence and types of connections between nodes. The algorithm developed from the method is tested by applying to a simulated ErbB signaling cascade model.en_US
dc.identifierhttps://doi.org/10.13016/M2S03X
dc.identifier.urihttp://hdl.handle.net/1903/16294
dc.language.isoenen_US
dc.subject.pqcontrolledElectrical engineeringen_US
dc.subject.pquncontrollednetwork connectivityen_US
dc.subject.pquncontrolledorganen_US
dc.subject.pquncontrolledsignal processingen_US
dc.subject.pquncontrolledwavelet analysisen_US
dc.titleDetermination of Network Connectivity: Algorithms and Applications in Organ Systemsen_US
dc.typeDissertationen_US

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