Glutamine supplementation and renal health
Glutamine supplementation and renal health
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Date
2009-05
Authors
Ahmad, Daniel
Bansal, Megha
Dillon, Elizabeth
Dorsey, Shauna
Jawed, Aysha
Katz, Perry
Newton, Andy
Palagois, Ashley
Sahu, Anita
Sharkey, Curtis
Advisor
Rogers, Marc
Citation
DRUM DOI
Abstract
Team Juiced designed a multi-faceted research project surrounding the potential risk of college students using protein supplements developing kidney disease. Survey research showed that participants taking protein supplements were ingesting double the recommended allowance based on literature values for average American dietary protein intake. Participants predisposed to kidney disease were no less likely to take protein supplements. Kidney cell modeling showed the molecular response to glutamine, an important protein building block. A significant increase in the gene expression of low-density lipoprotein receptor and two sclerotic markers was found in response to glutamine exposure. Gene expression was time- and dose-dependent. Enzymatic degradation and high performance liquid chromatography showed that three popular protein supplements contained more glutamine than stated by the manufacturers.
Notes
Gemstone Team Juiced