Antioxidant and Anti-proliferative properties of selected grape seed extracts

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dc.contributor.advisorYu, Lianglien_US
dc.contributor.authorBloom, Raquel Zorahen_US
dc.contributor.departmentNutritionen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2009-07-03T05:39:04Z
dc.date.available2009-07-03T05:39:04Z
dc.date.issued2009en_US
dc.description.abstractThis study examined chardonnay, muscadine, concord, and ruby red grape seed oil and flour extracts for antioxidant and anti-proliferative properties. The extracts were tested for total phenolic content, DPPH* · and ABTS*+ ·radical scavenging capacity and effect against HT-29 cancer cell proliferation. All of the grape seed extracts exhibited ABTS*+ · and DPPH*· radical quenching activity. The flour extracts from chardonnay demonstrated the highest ABTS*+· radical quenching capacity of 186 μμmoles trolox equivalents/g and DPPH* · radical quenching activity of 30 μμmoles trolox equivalents/g. All of the grape seed oil and flour extracts contained significant levels of phenolics. Chardonnay grape seed flour extract displayed the most prominent dose dependent anti-proliferative effect. Muscadine and ruby red, but not concord grape seed flour extracts, also exhibited anti-proliferative activities. The collected data advocate for the potential of grape seed extracts as dietary sources of anti-proliferative and antioxidant components.en_US
dc.format.extent844006 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/1903/9329
dc.language.isoen_US
dc.subject.pqcontrolledAgriculture, Food Science and Technologyen_US
dc.subject.pquncontrolledanti-proliferativeen_US
dc.subject.pquncontrolledantioxidanten_US
dc.subject.pquncontrolledcanceren_US
dc.subject.pquncontrolledcolorectalen_US
dc.subject.pquncontrolledgrape seeden_US
dc.subject.pquncontrolledht-29en_US
dc.titleAntioxidant and Anti-proliferative properties of selected grape seed extractsen_US
dc.typeThesisen_US

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