MILK AND BLOOD CONCENTRATIONS OF LIPOPOLYSACCHARIDE-BINDING PROTEIN IN COWS WITH NATURALLY-OCCURRING SUBCLINICAL AND CLINICAL MASTITIS

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dc.contributor.advisorBequette, Brian Jen_US
dc.contributor.authorZENG, RONGYUen_US
dc.contributor.departmentAnimal Sciencesen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2008-10-11T05:53:03Z
dc.date.available2008-10-11T05:53:03Z
dc.date.issued2008-08-22en_US
dc.description.abstractThe objective of this thesis was to evaluate the blood and milk concentrations of lipopolysaccharide-binding protein (LBP) from cows with naturally-occurring mastitis as biomarkers of this disease. Milk and blood samples were collected from 101 clinically healthy dairy cows and 17 dairy cows with clinical mastitis. The concentrations of LBP, haptoglobin and serum amyloid A (SAA) were determined in these samples by enzyme-linked immunosorbent assay. Both LBP and haptoglobin concentrations were higher in the milk and blood of quarters and cows with clinical mastitis respectively than in those that were healthy. Whereas haptoglobin concentrations differed between uninfected and subclinically-infected quarters, LBP concentrations only differed between them when milk somatic cell counts were low. Unlike haptoglobin and SAA, blood concentrations of LBP in cows with a subclinical intramammary infection were not significant from those of cows with all healthy quarters. Thus, haptoglobin may be a preferred biomarker of subclinical intramammary infection.en_US
dc.format.extent344262 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/1903/8628
dc.language.isoen_US
dc.subject.pqcontrolledBiology, Veterinary Scienceen_US
dc.titleMILK AND BLOOD CONCENTRATIONS OF LIPOPOLYSACCHARIDE-BINDING PROTEIN IN COWS WITH NATURALLY-OCCURRING SUBCLINICAL AND CLINICAL MASTITISen_US
dc.typeThesisen_US

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