The Effect of Dietary Tartrazine on Brain Dopamine and the Behavioral Symptoms of Attention Deficit Hyperactivity Disorder

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dc.contributor.advisorCastonguay, Thomas W.
dc.contributor.authorBloom, Shoshana
dc.contributor.authorChiang, Kevin
dc.contributor.authorDemehri, Sharlene
dc.contributor.authorKreshpanji, Sara
dc.contributor.authorMcCaffrey, Erin
dc.contributor.authorPatel, Karishma
dc.contributor.authorSebastian, Tracy
dc.contributor.authorShan, Salwa
dc.contributor.authorSukri, Leah
dc.date.accessioned2016-06-15T15:05:11Z
dc.date.available2016-06-15T15:05:11Z
dc.date.issued2016-05
dc.description.abstractAttention Deficit Hyperactivity Disorder is a neurodevelopmental disorder correlated with a decrease in brain dopamine and an increase in behavioral symptoms of hyperactivity and impulsivity. This experiment explored how tartrazine (Yellow #5) impacts these symptoms. After tartrazine administration to Spontaneously Hypertensive Rats (SHR), dopamine concentrations in regions of brain tissue were measured using Enzyme-Linked Immunosorbent Assay analysis. Behavioral testing with a T-maze and open field test measured impulsivity and hyperactivity, respectively. Results indicate that dietary tartrazine increases hyperactive behaviors in the SHR. However, results do not indicate a relationship between dietary tartrazine and brain dopamine. No conclusions regarding the relationship between dietary tartrazine and impulsivity were drawn.en_US
dc.identifierhttps://doi.org/10.13016/M2VB64
dc.identifier.urihttp://hdl.handle.net/1903/18096
dc.language.isoen_USen_US
dc.relation.isAvailableAtDigital Repository at the University of Maryland
dc.relation.isAvailableAtGemstone Program, University of Maryland (College Park, Md)
dc.subjectGemstone Team ATTENTen_US
dc.subjectAttention Deficit Hyperactivity Disorderen_US
dc.subjecttartrazineen_US
dc.subjectbrain dopamine
dc.titleThe Effect of Dietary Tartrazine on Brain Dopamine and the Behavioral Symptoms of Attention Deficit Hyperactivity Disorderen_US
dc.typeThesisen_US

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