ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISMS WITH PHENOTYPIC PRODUCTION TRAITS IN BROILER CHICKENS

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dc.contributor.advisorPorter, Tom Een_US
dc.contributor.authorLiu, Xuanen_US
dc.contributor.departmentAnimal Sciencesen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2009-10-06T06:40:49Z
dc.date.available2009-10-06T06:40:49Z
dc.date.issued2009en_US
dc.description.abstractThis research investigated the association between SNPs and phenotypic production traits in fat and lean chicken broiler lines. In previous research, eleven SNPs in the promoter regions of four candidate genes were selected. In this study, significant associations were detected between AKR1B10 SNP1 and SDC1 SNP1 and fat yield. SDC1 SNP1 was significantly associated with fat weight. SOD3 SNP2 was associated with breast yield. Five sire-SNP interactions and one sex-SNP interaction were significant. There was a significant interaction between sex and SDC1 SNP3 on muscle-related factor. GPC3 SNP1 interacted with time period on body weight from week 1 to week 9. QTLs on chromosomes 1, 3 and 4 for body fat were refined by incorporating these SNPs into QTL analysis. These genetic markers may be of great value for marker-assisted selection (MAS) for chickens with less abdominal fat as well as genetic markers for body fat accumulation in humans.en_US
dc.format.extent922564 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/1903/9653
dc.language.isoen_US
dc.subject.pqcontrolledBiology, Geneticsen_US
dc.subject.pqcontrolledBiology, Biostatisticsen_US
dc.subject.pquncontrolledbroiler chickenen_US
dc.subject.pquncontrolledfaten_US
dc.subject.pquncontrolledGPC3en_US
dc.subject.pquncontrolledSDC1en_US
dc.subject.pquncontrolledSNPen_US
dc.subject.pquncontrolledSOD3en_US
dc.titleASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISMS WITH PHENOTYPIC PRODUCTION TRAITS IN BROILER CHICKENSen_US
dc.typeThesisen_US

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