PRELIMINARY GENETIC CHARACTERIZATION OF RIBOSOMAL PROTEIN L10 IN SACCHAROMYCES CEREVISIAE

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dc.contributor.advisorDinman, Jonathan Den_US
dc.contributor.authorSimmons, Mary Kecia Rigsbyen_US
dc.contributor.departmentCell Biology & Molecular Geneticsen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2005-08-03T15:27:08Z
dc.date.available2005-08-03T15:27:08Z
dc.date.issued2005-05-27en_US
dc.description.abstractWhile recent research has focused on the exciting concept of the ribosome as a ribozyme, ribosomal proteins have been largely overlooked. This study focuses on four previously identified mutants of the ribosomal large subunit protein L10, in an effort to better understand how the protein's structure corresponds to its function. All of the mutants studied displayed how the embedded nature of L10 caused only slight conformational changes to impact function of the ribosome as a whole; in these cases primarily altering the interaction between the ribosomal A-site and aminoacyl-tRNAs.en_US
dc.format.extent1699532 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/1903/2659
dc.language.isoen_US
dc.subject.pqcontrolledBiology, Molecularen_US
dc.subject.pqcontrolledBiology, Geneticsen_US
dc.subject.pquncontrolledribosomeen_US
dc.subject.pquncontrolledPRFen_US
dc.subject.pquncontrolledribosomal proteinen_US
dc.titlePRELIMINARY GENETIC CHARACTERIZATION OF RIBOSOMAL PROTEIN L10 IN SACCHAROMYCES CEREVISIAEen_US
dc.typeThesisen_US

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