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Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human

dc.contributor.authorLiu, Shuli
dc.contributor.authorYu, Ying
dc.contributor.authorZhang, Shengli
dc.contributor.authorCole, John B.
dc.contributor.authorTenesa, Albert
dc.date.accessioned2021-04-05T16:43:36Z
dc.date.available2021-04-05T16:43:36Z
dc.date.issued2020-07-03
dc.identifierhttps://doi.org/10.13016/jz08-zcgh
dc.identifier.citationLiu, S., Yu, Y., Zhang, S. et al. Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human. BMC Biol 18, 80 (2020).en_US
dc.identifier.urihttp://hdl.handle.net/1903/26944
dc.description.abstractLack of comprehensive functional annotations across a wide range of tissues and cell types severely hinders the biological interpretations of phenotypic variation, adaptive evolution, and domestication in livestock. Here we used a combination of comparative epigenomics, genome-wide association study (GWAS), and selection signature analysis, to shed light on potential adaptive evolution in cattle.en_US
dc.description.urihttps://doi.org/10.1186/s12915-020-00792-6
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.subjectComparative epigenomicsen_US
dc.subjectGWAS enrichmenten_US
dc.subjectTrait-relevant tissuesen_US
dc.subjectHuman-cattle comparisonen_US
dc.titleEpigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and humanen_US
dc.typeArticleen_US
dc.relation.isAvailableAtCollege of Agriculture & Natural Resourcesen_us
dc.relation.isAvailableAtAnimal & Avian Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us


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