dc.contributor.advisor | Castonguay, Thomas W. | |
dc.contributor.author | Bloom, Shoshana | |
dc.contributor.author | Chiang, Kevin | |
dc.contributor.author | Demehri, Sharlene | |
dc.contributor.author | Kreshpanji, Sara | |
dc.contributor.author | McCaffrey, Erin | |
dc.contributor.author | Patel, Karishma | |
dc.contributor.author | Sebastian, Tracy | |
dc.contributor.author | Shan, Salwa | |
dc.contributor.author | Sukri, Leah | |
dc.date.accessioned | 2016-06-15T15:05:11Z | |
dc.date.available | 2016-06-15T15:05:11Z | |
dc.date.issued | 2016-05 | |
dc.identifier | https://doi.org/10.13016/M2VB64 | |
dc.identifier.uri | http://hdl.handle.net/1903/18096 | |
dc.description.abstract | Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder
correlated with a decrease in brain dopamine and an increase in behavioral symptoms
of hyperactivity and impulsivity. This experiment explored how tartrazine (Yellow
#5) impacts these symptoms. After tartrazine administration to Spontaneously
Hypertensive Rats (SHR), dopamine concentrations in regions of brain tissue were
measured using Enzyme-Linked Immunosorbent Assay analysis. Behavioral testing
with a T-maze and open field test measured impulsivity and hyperactivity,
respectively. Results indicate that dietary tartrazine increases hyperactive behaviors in
the SHR. However, results do not indicate a relationship between dietary tartrazine
and brain dopamine. No conclusions regarding the relationship between dietary
tartrazine and impulsivity were drawn. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Gemstone Team ATTENT | en_US |
dc.subject | Attention Deficit Hyperactivity Disorder | en_US |
dc.subject | tartrazine | en_US |
dc.subject | brain dopamine | |
dc.title | The Effect of Dietary Tartrazine on Brain Dopamine and the Behavioral Symptoms of Attention Deficit Hyperactivity Disorder | en_US |
dc.type | Thesis | en_US |
dc.relation.isAvailableAt | Digital Repository at the University of Maryland | |
dc.relation.isAvailableAt | Gemstone Program, University of Maryland (College Park, Md) | |