Office of Undergraduate Research

Permanent URI for this communityhttp://hdl.handle.net/1903/20157

Emphasizing equitable and inclusive access to research opportunities, the University of Maryland's Office of Undergraduate Research (OUR) empowers undergraduates and faculty to engage and succeed in inquiry, creative activity, and scholarship. This collection includes materials shared by undergraduate researchers during OUR events. It also encompasses materials from Undergraduate Research Day 2020, Undergraduate Research Day 2021, and Undergraduate Research Day 2022, which were organized by the Maryland Center for Undergraduate Research.

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Subject: search.filters.subject.Antibiotic Resistance

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    Effects of the aceE Gene on E. coli Growth and Bacteriophage Replication
    (2024) Lippert, Celia; Lynskey, Julie Anne; Lee, James; Dasgupta, Ruben; O'Hara Jessica
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    Spread Prevention and Eradication of Resistant Bacterial Growth
    (2024) Sripathi, Neha; Kim, Joshua; Dinh, Phuclam; Rayford, Amber; Breymaier, Nicholas; Zhang, Cristina; Hillman, Mackenzie; Stein, Daniel; Stein, Daniel
    Diseases caused by drug resistant bacteria are becoming a pressing public health threat due to a lack of new antibiotics and the evolution of multidrug resistance. Drug resistance is caused by mutant or novel genes known as resistance genes. CRISPR-Cas9 gene editing has been shown in recent studies to successfully edit resistance genes to increase susceptibility to antibiotics. We aim to use bacteriophage M13 to transduce a CRISPR-Cas9 system into nalidixic acid resistant Escherichia coli and resensitize it to nalidixic acid. We aim to improve upon the efficiency of previous studies.