Yanagi: Fast and interpretable segment-based alternative splicing and gene expression analysis

dc.contributor.authorGunady, Mohamed K
dc.contributor.authorMount, Stephen M
dc.contributor.authorBravo, Héctor Corrada
dc.date.accessioned2021-06-07T16:04:00Z
dc.date.available2021-06-07T16:04:00Z
dc.date.issued2019-08-13
dc.description.abstractUltra-fast pseudo-alignment approaches are the tool of choice in transcript-level RNA sequencing (RNA-seq) analyses. Unfortunately, these methods couple the tasks of pseudo-alignment and transcript quantification. This coupling precludes the direct usage of pseudo-alignment to other expression analyses, including alternative splicing or differential gene expression analysis, without including a non-essential transcript quantification step.en_US
dc.description.urihttps://doi.org/10.1186/s12859-019-2947-6
dc.identifierhttps://doi.org/10.13016/kpug-smuf
dc.identifier.citationGunady, M.K., Mount, S.M. & Corrada Bravo, H. Yanagi: Fast and interpretable segment-based alternative splicing and gene expression analysis. BMC Bioinformatics 20, 421 (2019).en_US
dc.identifier.urihttp://hdl.handle.net/1903/27120
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Computer, Mathematical & Natural Sciencesen_us
dc.relation.isAvailableAtComputer Scienceen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectTranscriptome quantificationen_US
dc.subjectDifferential gene expressionen_US
dc.subjectAlternative splicingen_US
dc.subjectRNA-seqen_US
dc.subjectPseudo-alignmenten_US
dc.titleYanagi: Fast and interpretable segment-based alternative splicing and gene expression analysisen_US
dc.typeArticleen_US

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