Spread Prevention and Eradication of Resistant Bacterial Growth

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dc.contributor.advisorStein, Daniel
dc.contributor.authorSripathi, Neha
dc.contributor.authorKim, Joshua
dc.contributor.authorDinh, Phuclam
dc.contributor.authorRayford, Amber
dc.contributor.authorBreymaier, Nicholas
dc.contributor.authorZhang, Cristina
dc.contributor.authorHillman, Mackenzie
dc.contributor.authorStein, Daniel
dc.date.accessioned2024-04-07T19:38:56Z
dc.date.available2024-04-07T19:38:56Z
dc.date.issued2024
dc.description.abstractDiseases caused by drug resistant bacteria are becoming a pressing public health threat due to a lack of new antibiotics and the evolution of multidrug resistance. Drug resistance is caused by mutant or novel genes known as resistance genes. CRISPR-Cas9 gene editing has been shown in recent studies to successfully edit resistance genes to increase susceptibility to antibiotics. We aim to use bacteriophage M13 to transduce a CRISPR-Cas9 system into nalidixic acid resistant Escherichia coli and resensitize it to nalidixic acid. We aim to improve upon the efficiency of previous studies.
dc.description.sponsorshipLaunch UMD
dc.identifierhttps://doi.org/10.13016/ewxj-c4xj
dc.identifier.urihttp://hdl.handle.net/1903/32405
dc.language.isoen_US
dc.relation.isAvailableAtDigital Repository at the University of Maryland
dc.relation.isAvailableAtUniversity of Maryland (College Park, Md)
dc.relation.isAvailableAtOffice of Undergraduate Research
dc.rightsCC0 1.0 Universalen
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.subjectCell Biology & Molecular Genetics
dc.subjectCMNS
dc.subjectGemstone
dc.subjectTeam SUPERBUG
dc.subjectBiology
dc.subjectMicrobiology
dc.subjectAntibiotic Resistance
dc.titleSpread Prevention and Eradication of Resistant Bacterial Growth
dc.typeOther
local.equitableAccessSubmissionNo

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