Serum 25-Hydroxyvitamin D Concentration and Subsequent Risk of Type 2 Diabetes

Abstract

It has been suggested that vitamin D reduces the risk of type 2 diabetes. The finding that vitamin D deficiency is associated with impaired -cell function and insulin resistance in animals (1,2) and humans (3,4) is in line with that hypothesis. In the only cohort study published, the intake of vitamin D supplements was inversely associated with the development of type 2 diabetes (5). Since vitamin D intake covers only a part of the total vitamin D available, the purpose of this study was to evaluate the prediction of serum 25-hydroxyvitaminD (25OHD) on