Nanochannel fabrication using thermo-mechanical deformation of thermoplastics

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dc.contributor.advisorDeVoe, Donalden_US
dc.contributor.authorSahasrabudhe, Kapilen_US
dc.contributor.departmentMechanical Engineeringen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2007-02-01T20:23:31Z
dc.date.available2007-02-01T20:23:31Z
dc.date.issued2006-12-08en_US
dc.description.abstractNanofluidics has been a major field of research for application in areas like single molecule detection. Most of the research efforts have been concentrated in developing novel nanochannel fabrication techniques. Most of these fabrication techniques developed are either expensive or time consuming. A novel, low-cost fabrication technique to generate sub-micrometer wide channels in thermoplastic chips with potential application in single molecule detection is demonstrated. This nanochannel fabrication technique is based on thermo-mechanical deformation of a section of microchannel in thermoplastic chip to nanometer dimensions. A custom, mechanical rig was designed, fabricated and optimized to produce a pre-defined thermo-mechanical deformation in thermo-plastic microchannel chips. Rectangular microchannels with different shapes and sizes were deformed using this rig to optimize the initial microchannel dimensions. Low aspect ratio (height:width) channels with smaller initial dimensions exhibit more potential to reach sub-micrometer widths. However, the nanochannel fabrication consistency was adversely affected by manufacturing and assembly tolerances.en_US
dc.format.extent4081581 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/1903/4202
dc.language.isoen_US
dc.subject.pqcontrolledEngineering, Mechanicalen_US
dc.subject.pquncontrolledNanochannelen_US
dc.subject.pquncontrolledthermoplasticsen_US
dc.subject.pquncontrolledthermo-mechanicalen_US
dc.titleNanochannel fabrication using thermo-mechanical deformation of thermoplasticsen_US
dc.typeThesisen_US

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