High-Speed Reconstruction of Low-Dose CT Using Iterative Techniques for Image-Guided Interventions

Abstract

Minimally invasive image-guided interventions(IGIs) lead to improved treatment outcomes while significantly reducing patient trauma. Because of features such as fast scanning, high resolution, three-dimensional view and ease of operation, Computed-Tomography(CT) is increasingly the choice for IGIs. The risk of radiation exposure, however, limits its current and future use. We perform ultra low-dose scanning to overcome this limitation. To address the image quality problem at low doses, we reconstruct images using the iterative Paraboloidal Surrogate(PS) algorithm. Using actual scanner data, we demonstrate improvement in the quality of reconstructed images using the iterative algorithm at low doses as compared to the standard Filtered Back Projection(FBP) technique. We also accelerate the PS algorithm on a cluster of 32 processors and a GPU. We demonstrate approximately 20 times speedup for the cluster and two orders of improvement in speed for the GPU, while maintaining comparable image quality to the traditional uni-processor implementation.