INTERPRETABLE MACHINE VISION INTELLIGENCE METHODS FOR BIOPHARMACEUTICAL AND AGRICULTURAL MANUFACTURING AUTOMATION

dc.contributor.advisorTao, Yangen_US
dc.contributor.authorHevaganinge, Anjanaen_US
dc.contributor.departmentBioengineeringen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2025-09-12T05:34:20Z
dc.date.issued2025en_US
dc.description.abstractWithin the context of mission critical applications, there is growing concern in the trustworthiness and reliability of Artificial Intelligence (AI) driven automation techniques. In fact, the manufacturing sector is missing adaptable and interpretable AI driven systems that work synergistically with human intelligence and cognition. Thus, the development of such systems will be explored in both biopharmaceutical and seafood industries. (Biopharmaceutical Industry) As of 2016, 5 of the top 10 drugs were manufactured inside of a bioreactor and amounted to 75 billion dollars in annual sales. This market share has only grown since, but there are several upstream/downstream quality issues that stem from the current lack of a continuous control system. The development of a contactless and interpretable sensor to replace current invasive probes will enable adaptive multiplex sensing of critical material attributes (CMAs) and critical product attributes (CPAs) alike for precise real-time control of bioreactor environment to suit even the most delicate cells. On the other hand, (Seafood Industry) robots that can replicate human hand movements with surgical precision have the potential to alleviate manufacturing labor shortages, enhance rehabilitation technologies, and revolutionize procedures in operating rooms. Lump meat extraction from Maryland Blue Crabs represents a class of dexterous human tasks that are difficult to simulate, slow down or tele-operate . Thus, crab picking may be used as an excellent test bed for the development of a precise and interpretable surgical trajectory automation system. Both projects lead to the development of interpretable automation methods for both cell bioprocess cultivation and crab picking surgical motions. Unlike opaque machine learning models, interpretable models foster a trusting and collaborative relationship between the human practitioner and AI enabled machine. So, the developed methods can be extended to other high-stake tasks that directly impact human health and cost of living.en_US
dc.identifierhttps://doi.org/10.13016/0l5t-lqvi
dc.identifier.urihttp://hdl.handle.net/1903/34509
dc.language.isoenen_US
dc.subject.pqcontrolledArtificial intelligenceen_US
dc.subject.pqcontrolledRoboticsen_US
dc.subject.pqcontrolledBioengineeringen_US
dc.titleINTERPRETABLE MACHINE VISION INTELLIGENCE METHODS FOR BIOPHARMACEUTICAL AND AGRICULTURAL MANUFACTURING AUTOMATIONen_US
dc.typeDissertationen_US

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