Cell Maps on the Human Genome

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dc.contributor.authorCherniak, Christopher
dc.contributor.authorRodriguez-Esteban, Raul
dc.date.accessioned2018-10-28T14:38:28Z
dc.date.available2018-10-28T14:38:28Z
dc.date.issued2018-06-01
dc.description.abstractSub-cellular organization is significantly mapped onto the human genome: Evidence is reported for a "cellunculus" -- on the model of a homunculus, on the H. sapiens genome. We have previously described a statistically significant, global, supra-chromosomal representation of the human body that appears to extend over the entire genome. Here, we extend the genome mapping model, zooming down to the typical individual animal cell. Basic cell structure turns out to map onto the total genome, mirrored via genes that express in particular cell organelles (e.g., “nuclear membrane”); evidence also suggests similar cell maps appear on individual chromosomes that map the dorsoventral body axis.en_US
dc.identifierhttps://doi.org/10.13016/M26H4CT9V
dc.identifier.urihttp://hdl.handle.net/1903/21457
dc.language.isoen_USen_US
dc.relation.ispartofseriesUMIACS;UMIACS-TR-2018-01
dc.relation.ispartofseriesUM Computer Science Department;CS-TR-5060
dc.subjectgenomeen_US
dc.subjectsomatotopic mapen_US
dc.subjecthomunculusen_US
dc.subjectcellunculusen_US
dc.subjectorganelle-specific geneen_US
dc.subjectconnection optimizationen_US
dc.titleCell Maps on the Human Genomeen_US
dc.typeTechnical Reporten_US

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