Genome assembly forensics: finding the elusive mis-assembly
| dc.contributor.author | Phillippy, Adam M | |
| dc.contributor.author | Schatz, Michael C | |
| dc.contributor.author | Pop, Mihai | |
| dc.date.accessioned | 2021-12-06T18:33:26Z | |
| dc.date.available | 2021-12-06T18:33:26Z | |
| dc.date.issued | 2008-03-14 | |
| dc.description.abstract | We present the first collection of tools aimed at automated genome assembly validation. This work formalizes several mechanisms for detecting mis-assemblies, and describes their implementation in our automated validation pipeline, called amosvalidate. We demonstrate the application of our pipeline in both bacterial and eukaryotic genome assemblies, and highlight several assembly errors in both draft and finished genomes. The software described is compatible with common assembly formats and is released, open-source, at http://amos.sourceforge.net . | en_US |
| dc.description.uri | https://doi.org/10.1186/gb-2008-9-3-r55 | |
| dc.identifier | https://doi.org/10.13016/neuj-yv5z | |
| dc.identifier.citation | Phillippy, A.M., Schatz, M.C. & Pop, M. Genome assembly forensics: finding the elusive mis-assembly. Genome Biol 9, R55 (2008). | en_US |
| dc.identifier.uri | http://hdl.handle.net/1903/28198 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Springer Nature | en_US |
| dc.relation.isAvailableAt | College of Computer, Mathematical & Physical Sciences | en_us |
| dc.relation.isAvailableAt | Digital Repository at the University of Maryland | en_us |
| dc.relation.isAvailableAt | Biology | en_us |
| dc.relation.isAvailableAt | University of Maryland (College Park, MD) | en_us |
| dc.subject | Bacterial Artificial Chromosome | en_US |
| dc.subject | Additional Data File | en_US |
| dc.subject | Repeat Copy | en_US |
| dc.subject | Assembly Quality | en_US |
| dc.subject | Suspicious Region | en_US |
| dc.title | Genome assembly forensics: finding the elusive mis-assembly | en_US |
| dc.type | Article | en_US |