Genome assembly forensics: finding the elusive mis-assembly

dc.contributor.authorPhillippy, Adam M
dc.contributor.authorSchatz, Michael C
dc.contributor.authorPop, Mihai
dc.date.accessioned2021-12-06T18:33:26Z
dc.date.available2021-12-06T18:33:26Z
dc.date.issued2008-03-14
dc.description.abstractWe present the first collection of tools aimed at automated genome assembly validation. This work formalizes several mechanisms for detecting mis-assemblies, and describes their implementation in our automated validation pipeline, called amosvalidate. We demonstrate the application of our pipeline in both bacterial and eukaryotic genome assemblies, and highlight several assembly errors in both draft and finished genomes. The software described is compatible with common assembly formats and is released, open-source, at http://amos.sourceforge.net .en_US
dc.description.urihttps://doi.org/10.1186/gb-2008-9-3-r55
dc.identifierhttps://doi.org/10.13016/neuj-yv5z
dc.identifier.citationPhillippy, A.M., Schatz, M.C. & Pop, M. Genome assembly forensics: finding the elusive mis-assembly. Genome Biol 9, R55 (2008).en_US
dc.identifier.urihttp://hdl.handle.net/1903/28198
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Computer, Mathematical & Physical Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtBiologyen_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectBacterial Artificial Chromosomeen_US
dc.subjectAdditional Data Fileen_US
dc.subjectRepeat Copyen_US
dc.subjectAssembly Qualityen_US
dc.subjectSuspicious Regionen_US
dc.titleGenome assembly forensics: finding the elusive mis-assemblyen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
gb-2008-9-3-r55.pdf
Size:
965.04 KB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.57 KB
Format:
Item-specific license agreed upon to submission
Description: