Disinfection Ability of Bacteriophages Against Listeria Monocytogenes Biofilms

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dc.contributor.advisorBiswas, Debabrata
dc.contributor.authorFrail, Sarah
dc.contributor.authorLiu, Gina
dc.contributor.authorMacatee, Grace
dc.contributor.authorMavanur, Tejas
dc.contributor.authorOchieng, Kerina
dc.contributor.authorPurdy, Cara
dc.contributor.authorShan, Patrick
dc.contributor.authorTran, Thomas
dc.contributor.authorWain, Sarah
dc.date.accessioned2018-06-22T17:40:06Z
dc.date.available2018-06-22T17:40:06Z
dc.date.issued2018
dc.description.abstractPathogenic foodborne bacteria, particularly species belonging to Listeria and Salmonella, pose a growing threat to public health because of their ability to form and/or grow within biofilms on various environments, specifically food processing facility. Within a biofilm, bacteria develop increased resistance to common disinfectants, making surface sterilization a challenge for businesses involved in food processing. In order to determine the viability of bacteriophages as an antibiotic alternative, this experiment attempted to explore the bacteriophage growth process as well as bacteriophage efficacy against Listeria monocyogenes as compared to Salmonella enterica serovar Typhimurium. A511 bacteriophage was grown and tested on L. monocytogenes 1/2a using previously studied P22 bacteriophage and S. enterica as a control case. While this experiment was unable to establish a defined efficacy of A511 against L. monocytogenes, repeatable results with Salmonella show promising potential for phage therapies.en_US
dc.identifierhttps://doi.org/10.13016/M2TX3592M
dc.identifier.urihttp://hdl.handle.net/1903/20675
dc.language.isoen_USen_US
dc.relation.isAvailableAtDigital Repository at the University of Maryland
dc.relation.isAvailableAtGemstone Program, University of Maryland (College Park, Md)
dc.subjectGemstone Team PHAGEen_US
dc.titleDisinfection Ability of Bacteriophages Against Listeria Monocytogenes Biofilmsen_US
dc.typeThesisen_US

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