University of Maryland LibrariesDigital Repository at the University of Maryland
    • Login
    View Item 
    •   DRUM
    • Theses and Dissertations from UMD
    • UMD Theses and Dissertations
    • View Item
    •   DRUM
    • Theses and Dissertations from UMD
    • UMD Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Miniature Fiber Optic Pressure Sensors for Intervertebral Disc Pressure Measurements in Rodents

    Thumbnail
    View/Open
    umi-umd-4810.pdf (3.184Mb)
    No. of downloads: 3009

    Date
    2007-08-13
    Author
    Nesson, Silas Carl
    Advisor
    Yu, Miao
    Metadata
    Show full item record
    Abstract
    Mechanical stress due to interstitial fluid pressures can play a major role in the development of disc degeneration, a common cause of lower back pain. Pressures generated in the intervertebral disc have previously been measured in humans and animals. However, due to their small size, thus far it has been difficult to experimentally measure pressures in rodents. With the prevalent use of rodent disc models in mechanobiology, it is important to characterize the intradiscal pressures under externally applied stresses. In this thesis research, two different optical systems with novel miniature fiber optic pressure sensors have been developed. These systems are an intensity based solid-tip sensor system and a low coherence Fabry-Perot sensor system. Pressure sensors, which have diameters of only 363 µm, were designed to measure pressures in rat discs without disrupting the structure and altering the intradiscal pressures. For the first time, in vitro intradiscal pressure measurements of rodents have been successfully demonstrated by using these sensors.
    URI
    http://hdl.handle.net/1903/7394
    Collections
    • Mechanical Engineering Theses and Dissertations
    • UMD Theses and Dissertations

    DRUM is brought to you by the University of Maryland Libraries
    University of Maryland, College Park, MD 20742-7011 (301)314-1328.
    Please send us your comments.
    Web Accessibility
     

     

    Browse

    All of DRUMCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister
    Pages
    About DRUMAbout Download Statistics

    DRUM is brought to you by the University of Maryland Libraries
    University of Maryland, College Park, MD 20742-7011 (301)314-1328.
    Please send us your comments.
    Web Accessibility