• Design of Self-Assembling Nanostructures to Promote Immune Tolerance 

  Hess, Krystina (2018)

  In autoimmune diseases, which affect more than 23 million Americans, the immune system mistakenly attacks healthy tissue. This occurs when the process that normally controls self-reactive inflammatory cells (i.e. tolerance) ...

• Optical and Thermal Systems for Automation of Point-of-Care Assays 

  Goertz, John (2018)

  Modern medicine has detailed 70,000 different diagnoses; the 21st century challenge is bringing those diagnoses to over 7 billion people. This phenomenal feat requires precision biosensing strategies that minimize necessary ...

• PROTEIN AND PEPTIDE ENGINEERING FOR IMPROVING THERAPIES FOR APPLICATIONS IN HUMAN HEALTH 

  Moghaddam-Taaheri, Parisa (2018)

  The work in this dissertation focuses on protein and peptides engineering for improving therapies for applications in human health. First, we describe a directed evolution approach to engineer antibody fragments to bind ...

• ENGINEERING CELLULAR MICROENVIRONMENT FOR CARTILAGE REGENERATION 

  Guo, Ting (2018)

  Articular cartilage defects, resulting from trauma or pathological change, affect a large population worldwide from adolescents to adults. The limited self-renewal ability of cartilage due to lack of blood vessels and ...

• DEVELOPING AN IN SITU SPRAYABLE BIOSCAFFOLD WITH ANTIMICROBIAL PROPERTIES AS AN EMERGENCY BURN WOUND DRESSING 

  Hunter, Joseph William (2018)

  Commercially available silver dressings and their associated application/removal protocols suffer from several serious drawbacks, including: inability to monitor the burn wound beneath the opaque dressing, high costs, ...

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