A. James Clark School of Engineering
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Protein-based vehicles for biomimetic RNAi delivery
(Springer Nature, 2019-02-26)Broad translational success of RNA interference (RNAi) technology depends on the development of effective delivery approaches. To that end, researchers have developed a variety of strategies, including chemical modification ... -
Breaking the selectivity-uptake trade-off of photoimmunoconjugates with nanoliposomal irinotecan for synergistic multi-tier cancer targeting
(Springer Nature, 2020-01-02)Photoimmunotherapy involves targeted delivery of photosensitizers via an antibody conjugate (i.e., photoimmunoconjugate, PIC) followed by light activation for selective tumor killing. The trade-off between PIC selectivity ... -
Quantitatively relating brain endothelial cell–cell junction phenotype to global and local barrier properties under varied culture conditions via the Junction Analyzer Program
(Springer Nature, 2020-02-11)The endothelial cell–cell junctions of the blood–brain barrier (BBB) play a pivotal role in the barrier’s function. Altered cell–cell junctions can lead to barrier dysfunction and have been implicated in several diseases. ... -
Silicon modulates multi-layered defense against powdery mildew in Arabidopsis
(Springer Nature, 2020-03-27)Silicon (Si) has been widely employed in agriculture to enhance resistance against pathogens in many crop plants. However, the underlying molecular mechanisms of Si-mediated resistance remain elusive. In this study, the ... -
Experimental Data from 'Direct Extraction of Signal and Noise Correlations from Two-Photon Calcium Imaging of Ensemble Neuronal Activity'
(2021-03)The deposited data set contain: 1) Simulated two-photon imaging data under stimulus-driven and spontaneous conditions 2) Two-photon imaging data from the mouse auditory cortices (Kanold Lab, UMD). Please refer to the ...