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dc.contributor.authorBaykousheva, S.
dc.date.accessioned2011-08-03T15:37:29Z
dc.date.available2011-08-03T15:37:29Z
dc.date.issued1988
dc.identifier.citationBaykousheva, S. 1988. Secretion of proteins by Bacillus subtilis 168 grown in the presence of membrane active agents (alcohols). Journal of Chromatography A 440 (C):379-383.en_US
dc.identifier.urihttp://hdl.handle.net/1903/11818
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0021967300945412
dc.description.abstractSodium dodecyl sulphate-polyacrylamide gel electrophoresis was used to study the composition of proteins secreted by the Gram-positive microorganism Bacillus subtilis strain 168 when the latter was grown in the presence of primary alcohols (methanol, ethanol, 1-propanol and 1-butanol). These membrane-active agents had different effects on the pattern of proteins exported by B. subtilis. The secretion of some proteins was inhibited by the alkanols while that of others was stimulated, depending on the type of drug used. All alcohols were found to decrease the activity of extracellular enzymes such as alpha-amylase and serine protease without affecting significantly the activity of these enzymes when tested in vitro. The observed effects might be due to the ability of these agents to perturb the structure of biological membranes, thus interfering with the process of protein translocation through the lipid bilayers.en_US
dc.language.isoenen_US
dc.subjectCell membraneen_US
dc.subjectBacillus subtilisen_US
dc.subjectBaykouchevaen_US
dc.subjectalcoholsen_US
dc.subjectproteinsen_US
dc.subjectsecretionen_US
dc.titleSecretion of proteins by Bacillus subtilis 168 grown in the presence of membrane active agents (alcohols)en_US
dc.typeArticleen_US
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland Librariesen_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us


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