Theses and Dissertations from UMD

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New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a give thesis/dissertation in DRUM

More information is available at Theses and Dissertations at University of Maryland Libraries.

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Author: search.filters.author.Simmons, Mary Kecia RigsbySubject: search.filters.subject.PRF

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    PRELIMINARY GENETIC CHARACTERIZATION OF RIBOSOMAL PROTEIN L10 IN SACCHAROMYCES CEREVISIAE
    (2005-05-27) Simmons, Mary Kecia Rigsby; Dinman, Jonathan D; Cell Biology & Molecular Genetics; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    While recent research has focused on the exciting concept of the ribosome as a ribozyme, ribosomal proteins have been largely overlooked. This study focuses on four previously identified mutants of the ribosomal large subunit protein L10, in an effort to better understand how the protein's structure corresponds to its function. All of the mutants studied displayed how the embedded nature of L10 caused only slight conformational changes to impact function of the ribosome as a whole; in these cases primarily altering the interaction between the ribosomal A-site and aminoacyl-tRNAs.