UMD Theses and Dissertations

Permanent URI for this collectionhttp://hdl.handle.net/1903/3

New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a given thesis/dissertation in DRUM.

More information is available at Theses and Dissertations at University of Maryland Libraries.

Browse

Filters

20041

Settings

Author: search.filters.author.Vogel, Abby JeanneSubject: search.filters.subject.Laser Doppler Imaging

Search Results

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    NON-INVASIVE IMAGING TECHNIQUES AS A QUANTITATIVE ANALYSIS OF SKIN DAMAGE DUE TO IONIZING RADIATION
    (2004-05-06) Vogel, Abby Jeanne; Tao, Yang; Biological Resources Engineering; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    This study tested the ability of two non-invasive techniques, thermography and near-infrared multi-spectral imaging, to quantitatively assess the response of mouse skin to a single dose of X-ray irradiation. Thermal images from an 8-12 micron thermal camera were recorded after a cold stimulation to see the thermal recovery of the skin. The irradiated areas showed a significantly faster thermal recovery than the non-irradiated areas two weeks after radiation (p < 0.05). The NIR multi-spectral imager obtained images at six specially selected wavelengths between 700 and 1000 nm. Two-layer model-based diffuse reflectance spectroscopy monitored changes in blood oxygen saturation and blood volume. Blood oxygen fractions were significantly lower after radiation (p < 0.05). Blood volume changed in six of seven irradiated mice one week after radiation. The non-invasive imaging techniques were successful in quantitatively analyzing the response of the skin to a single dose of irradiation.