Browsing by Author "Patel, Puja"
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Item Of Mice and Men: An Ergonomic and Market Assessment of Current Computer Mice(2010) Asendorf, Nick; Bonnington, Melissa; Lai, Kelly; Lehman, Allison; Mahadeo, Dinesh; Muench, Walter; Olver, Ryan; Patel, Puja; Ravichandran, Padma; Sichler, Jennifer; Hsieh, AdamWork-related Musculoskeletal Disorders (WMSDs) are conditions that develop over time due to repetitive motion and can painfully affect the fingers, wrist, arm, shoulder, back, and neck. Studies indicate a correlation between heavy computer mouse use and the prevalence of WMSDs. Our team evaluated current ergonomic mouse designs to determine which features of mice reduce excessive muscle activation and harmful arm and hand positioning while still maintaining ease of use and marketability. A motion capture system tracked arm and hand positioning, EMG analysis measured muscle activation, force sensors quantified the user‘s clicking force, and a Fitts‘ test evaluated mouse use efficiency. To determine the marketability of mice features, surveys generalized user preferences, while focus groups closely examined specific market factors. All these systems were combined to identify areas of improvement in ergonomic mouse design.Item Synbiotic-like effect of linoleic acid overproducing Lactobacillus casei with berry phenolic extracts against pathogenesis of enterohemorrhagic Escherichia coli(Springer Nature, 2019-07-27) Tabashsum, Zajeba; Peng, Mengfei; Bernhardt, Cassendra; Patel, Puja; Carrion, Michael; Biswas, DebabrataMajority of enteric infections are foodborne and antimicrobials including antibiotics have been used for their control and treatment. However, probiotics or prebiotics or their combination offer a potential alternative intervention strategy for improving the host health and preventing foodborne pathogen colonization/infections in reservoir. Further, bioengineered probiotics expressing bioactive products to achieve specific function is highly desirable. Recently, we over-expressed mcra (myosin cross-reactive antigen) gene in Lactobacillus casei (Lc) and developed a bioengineered probiotics Lc + CLA which produce higher amounts of metabolites including conjugated linoleic acid (CLA). Furthermore, we also reported that prebiotic like components such as berry pomace (byproduct) phenolic extracts (BPEs) can enhance the growth of probiotics and improved the beneficial effects of probiotics. In this study, we evaluated the antimicrobial effect of modified Lc + CLA in combination of BPEs on growth, survival and pathogenesis of enterohemorrhagic Escherichia coli (EHEC).