Effects of acute aerobic exercise on mnemonic discrimination performance in older adults
| dc.contributor.author | Callow, Daniel D. | |
| dc.contributor.author | Pena, Gabriel S. | |
| dc.contributor.author | Stark, Craig E. L. | |
| dc.contributor.author | Smith, J. Carson | |
| dc.date.accessioned | 2023-09-18T16:58:04Z | |
| dc.date.available | 2023-09-18T16:58:04Z | |
| dc.date.issued | 2022-08-15 | |
| dc.description.abstract | Objectives:Ample evidence suggests exercise is beneficial for hippocampal function. Furthermore, a single session of aerobic exercise provides immediate benefits to mnemonic discrimination performance, a highly hippocampal-specific memory process, in healthy younger adults. However, it is unknown if a single session of aerobic exercise alters mnemonic discrimination in older adults, who generally exhibit greater hippocampal deterioration and deficits in mnemonic discrimination performance. Methods: We conducted a within subject acute exercise study in 30 cognitively healthy and physically active older adults who underwent baseline testing and then completed two experimental visits in which they performed a mnemonic discrimination task before and after either 30 min of cycling exercise or 30 min of seated rest. Linear mixed-effects analyses were conducted in which condition order and age were controlled, time (pre vs. post) and condition (exercise vs. rest) were modeled as fixed effects, and subject as a random effect. Results: No significant time by condition interaction effect was found for object recognition (p = .254, η2 =.01), while a significant reduction in interference was found for mnemonic discrimination performance following the exercise condition (p = .012, η2 =.07). A post-intervention only analysis indicated that there was no difference between condition for object recognition (p = .186, η2 =.06), but that participants had better mnemonic discrimination performance (p < .001, η2 =.22) following the exercise. Conclusions: Our results suggest a single session of moderate-intensity aerobic exercise may reduce interference and elicit better mnemonic discrimination performance in healthy older adults, suggesting benefits for hippocampal-specific memory function. | |
| dc.description.uri | https://doi.org/10.1017/S1355617722000492 | |
| dc.identifier | https://doi.org/10.13016/dspace/uqt0-ukvv | |
| dc.identifier.citation | Callow, D., Pena, G., Stark, C., & Smith, J. (2023). Effects of acute aerobic exercise on mnemonic discrimination performance in older adults. Journal of the International Neuropsychological Society, 29(6), 519-528. | |
| dc.identifier.uri | http://hdl.handle.net/1903/30516 | |
| dc.language.iso | en_US | |
| dc.publisher | Cambridge University Press | |
| dc.relation.isAvailableAt | School of Public Health | en_us |
| dc.relation.isAvailableAt | Kinesiology | en_us |
| dc.relation.isAvailableAt | Digital Repository at the University of Maryland | en_us |
| dc.relation.isAvailableAt | University of Maryland (College Park, MD) | en_us |
| dc.subject | hippocampus | |
| dc.subject | memory | |
| dc.subject | physical activity | |
| dc.subject | cognition | |
| dc.subject | dentate gyrus | |
| dc.subject | cycling | |
| dc.title | Effects of acute aerobic exercise on mnemonic discrimination performance in older adults | |
| dc.type | Article | |
| local.equitableAccessSubmission | No |