Race/ethnic disparities in risk factor control and survival in the bypass angioplasty revascularization investigation 2 diabetes (BARI 2D) trial.

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dc.contributor.authorBeohar, Nirat
dc.contributor.authorSansing, Veronica V.
dc.contributor.authorDavis, Andrew M.
dc.contributor.authorSrinivas, V. S.
dc.contributor.authorHelmy, Tarek
dc.contributor.authorAlthouse, Andrew D.
dc.contributor.authorThomas, Stephen B.
dc.contributor.authorBrooks, Maria Mori
dc.date.accessioned2019-08-14T15:08:40Z
dc.date.available2019-08-14T15:08:40Z
dc.date.issued2013
dc.description.abstractThis study sought to evaluate the impact of race/ethnicity on cardiovascular risk factor control and on clinical outcomes in a setting of comparable access to medical care. The BARI 2D trial enrolled 1,750 participants from the United States and Canada that self-reported either White non-Hispanic (n [ 1,189), Black non-Hispanic (n =349), or Hispanic (n =212) race/ethnicity. Participants had type 2 diabetes and coronary artery disease and were randomized to cardiac and glycemic treatment strategies. All patients received intensive target-based medical treatment for cardiac risk factors. Average follow-up was 5.3 years. Kaplan-Meier survival curves and Cox proportional hazards regression models were constructed to assess potential differences in mortality and cardiovascular outcomes across racial/ethnic groups. Long-term risk of death and death/myocardial infarction/stroke did not vary significantly by race/ethnicity (5-year death: 11.0% Whites, 13.7% Blacks, 8.7% Hispanics, p =0.19; adjusted hazard ratio 1.18 Black versus White, 95% confidence interval 0.84 to 1.67, p = 0.33 and 0.82 Hispanic versus White, 95% confidence interval 0.51 to 1.34, p =0.43). Among the 1,168 patients with suboptimal risk factor control at baseline, the ability to attain better risk factor control during the trial was associated with higher 5-year survival (71%, 86% and 95% for patients with 0 or 1, 2, and 3 factors in control, respectively, p <0.001); this pattern was observed within each race/ethnic group. In conclusion, significant race/ethnic differences in cardiac risk profiles that persisted during follow-up did not translate into significant differences in 5-year death or death/MI/stroke.
dc.description.urihttps://www.ajconline.org/article/S0002-9149(13)01423-9/abstract
dc.identifierhttps://doi.org/10.13016/2uak-wbnp
dc.identifier.citationBeohar, Nirat and Sansing, Veronica V. and Davis, Andrew M. and Srinivas, V. S. and Helmy, Tarek and Althouse, Andrew D. and Thomas, Stephen B. and Brooks, Maria Mori (2013) Race/ethnic disparities in risk factor control and survival in the bypass angioplasty revascularization investigation 2 diabetes (BARI 2D) trial. American Journal of Cardiology, 112 (9). pp. 1298-1305.
dc.identifier.otherEprint ID 4219
dc.identifier.urihttp://hdl.handle.net/1903/24672
dc.subjectDisparities
dc.subjectChronic Illness & Diseases
dc.titleRace/ethnic disparities in risk factor control and survival in the bypass angioplasty revascularization investigation 2 diabetes (BARI 2D) trial.
dc.typeArticle

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