Comparative study of meningitis dynamics across nine African countries: a global perspective

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dc.contributor.authorBroutin, Hélène
dc.contributor.authorPhilippon, Solenne
dc.contributor.authorde Magny, Guillaume Constantin
dc.contributor.authorCourel, Marie-Françoise
dc.contributor.authorSultan, Benjamin
dc.contributor.authorGuégan, Jean-François
dc.date.accessioned2021-12-06T19:34:57Z
dc.date.available2021-12-06T19:34:57Z
dc.date.issued2007-07-10
dc.description.abstractMeningococcal meningitis (MM) represents an important public health problem especially in the "meningitis belt" in Africa. Although seasonality of epidemics is well known with outbreaks usually starting in the dry season, pluri-annual cycles are still less understood and even studied. In this context, we aimed at study MM cases time series across 9 sahelo-sudanian countries to detect pluri-annual periodicity and determine or not synchrony between dynamics. This global and comparative approach allows a better understanding of MM evolution in time and space in the long-term. We used the most adapted mathematical tool to time series analyses, the wavelet method. We showed that, despite a strong consensus on the existence of a global pluri-annual cycle of MM epidemics, it is not the case. Indeed, even if a clear cycle is detected in all countries, these cycles are not as permanent and regular as generally admitted since many years. Moreover, no global synchrony was detected although many countries seemed correlated. These results of the first large-scale study of MM dynamics highlight the strong interest and the necessity of a global survey of MM in order to be able to predict and prevent large epidemics by adapted vaccination strategy. International cooperation in Public Health and cross-disciplines studies are highly recommended to hope controlling this infectious disease.en_US
dc.description.urihttps://doi.org/10.1186/1476-072X-6-29
dc.identifierhttps://doi.org/10.13016/fhne-6yfi
dc.identifier.citationBroutin, H., Philippon, S., Constantin de Magny, G. et al. Comparative study of meningitis dynamics across nine African countries: a global perspective. Int J Health Geogr 6, 29 (2007).en_US
dc.identifier.urihttp://hdl.handle.net/1903/28205
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Computer, Mathematical & Natural Sciencesen_us
dc.relation.isAvailableAtComputer Scienceen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectMeningitisen_US
dc.subjectWavelet Analysisen_US
dc.subjectMass Vaccinationen_US
dc.subjectGlobal Synchronyen_US
dc.subjectMeningococcal Meningitisen_US
dc.titleComparative study of meningitis dynamics across nine African countries: a global perspectiveen_US
dc.typeArticleen_US

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