The Community Preventive Services Task Force recommends collaborative care for management of depressive disorders, based on strong evidence of effectiveness in improving depression symptoms, adherence to treatment, response to treatment, and remission and recovery from depression. The widespread prevalence of depressive disorders and the large disease burden from these disorders is well established. [1] and [2] Primary care remains the most frequent point of entry into the healthcare system for patients with depression symptoms, and nearly 60% of patients with depression continue to receive care at the primary care level.3 Hence, engagement in primary care to reduce morbidity and mortality from depression would include optimizing two processes: screening and treatment. The U.S. Preventive Services Task Force recommends screening for depression in adults (www.uspreventiveservicestaskforce.org/uspstf/uspsaddepr.htm) and adolescents (www.uspreventiveservicestaskforce.org/uspstf/uspschdepr.htm) in outpatient primary care settings, when adequate systems are in place for efficient diagnosis, treatment, and follow-up for depressive disorders.