Tech Reports in Computer Science and Engineering

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    Cell Maps on the Human Genome
    (2018-06-01) Cherniak, Christopher; Rodriguez-Esteban, Raul
    Sub-cellular organization is significantly mapped onto the human genome: Evidence is reported for a "cellunculus" -- on the model of a homunculus, on the H. sapiens genome. We have previously described a statistically significant, global, supra-chromosomal representation of the human body that appears to extend over the entire genome. Here, we extend the genome mapping model, zooming down to the typical individual animal cell. Basic cell structure turns out to map onto the total genome, mirrored via genes that express in particular cell organelles (e.g., “nuclear membrane”); evidence also suggests similar cell maps appear on individual chromosomes that map the dorsoventral body axis.