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Start date: 1976End date: 1979

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    On the phagocytosis in vitro of strains of Yersinia pseudotuberculosis after treatment with certain detergents and lipid solvents
    (Bulgarian Academy of Sciences, 1976) Baykousheva, S.; Veljanov, D.
    Reproduced from SciFinder with permission from the Chemical Abstracts Service. The addn. of Na lauryl sulfate [151-21-3] or petroleum ether to Y. pseudotuberculosis grown in a medium contg. 10% glycerol at 28° (conditions under which V and W antigens are not synthesized) significantly increased the phagocytosis of the bacterial cells by rabbit blood. The addn. of Na periodate or trypsin [9002-07-7] produced variable degrees of phagocytosis dependent on the virulence of the strains tested. The role of lipid synthesis in the restoration of phagocytosis at 28° is discussed.
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    Further studies on the metabolic changes in strains of Salmonella typhimurium and Yersinia pseudotuberculosis after treatment with some detergents and lipid solvents
    (1977) Veljanov, D; Radoucheva, T; Baykousheva, S; Kussovski, V
    Reproduced from SciFinder, with permission from the Chemical Abstracts Service. Incubation of S. typhimurium and Y. pseudotuberculosis in 30% petroleum ether at 37° inhibited respiration more than did 0.01-0.03% Na lauryl sulfate [151-21-3]. After a 72-h incubation in 10% glycerol [56-81-5] the respiration level returned to, or approached normal. Petroleum ether also inhibited dehydrogenase [9035-82-9] activity and glycolysis more than did Na lauryl sulfate. Incubation in glycerol also reversed this inhibition. Na lauryl sulfate completely and irreversibly inhibited phosphatase [9013-05-2] at pH 5.4 and 8.0. Petroleum ether inhibited phosphatase at pH 5.4 in Y. pseudotuberculosis and at pH 8.0 in S. typhimurium.
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    New concepts about phagocytosis
    (Bulgarian Academy of Sciences, 1979) Baykousheva, Svetla
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    Some biological properties of bacterial lipids
    (1977) Baykousheva, S; Veljanov, D
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    Glucose isomerase
    (1979) Baykousheva, S
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    Studies on the ultrastructure of Yersinia pseudotuberculosis after treatment with some detergents and solvents
    (Gustav Fischer Verlag, Stuttgart, 1977) Cherepova, Nadja; Baykousheva, Svetla; Veljanov, D
    The ultrastructural changes in 3 strains Yersinia pseudotuberculosis with different virulence after treatment with sodium lauryl sulfate (SLS) and petroleum ether were studied. The ultrafine sections after treatment with SLS show heavy destructive changes, concerning the cell wall, the cytoplasmic membrane and the inner structure of the cell. It was established that the same cells Y. pseudotuberculosis after cultivation on a medium with glycerol show a tendency to recover their ultrastructure. The cells treated with petroleum ether did not exhibit any notable ultrastructural changes.