Theses and Dissertations from UMD
Permanent URI for this communityhttp://hdl.handle.net/1903/2
New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a give thesis/dissertation in DRUM
More information is available at Theses and Dissertations at University of Maryland Libraries.
Browse
2 results
Search Results
Item THE LONGER-TERM IMPACT OF PERCEIVED DISCRIMINATION ON COUPLE RELATIONSHIP FUNCTIONING: EXAMINING PSYCHOLOGICAL AND PHYSIOLOGICAL PATHWAYS AMONG MIDDLE-AGED AND OLDER-AGED ADULTS IN THE UNITED STATES(2023) Du, Jingshuai; Quinn, Sandra SQ; Mittal, Mona MM; Family Studies; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)The current study aimed to investigate the longer-term impact of everyday discrimination and major lifetime discrimination at Time 1 (T1; 2008 and 2010) on couple relationship functioning at Time 3 (T3; 2016 and 2018) across 8 years. It also aimed to explore if psychological (measured by depressive symptoms) and physiological stress responses (measured by allostatic load) at Time 2 (T2; 2012 and 2014) mediated the longitudinal association between discrimination and couple relationship functioning among middle-aged and older-aged adults in the United States (U.S.). To answer the study aims, I conducted a longitudinal mediation path analysis (N = 2,344) in Mplus Version 8 using data from the Health and Retirement Study, an ongoing national survey of the health and aging experience of U.S. adults aged 51 and older residing in the community. The primary longitudinal mediation model with control variables demonstrated good model fit (χ2[4] = 21.78, p < 0.01, CFI = 0.99, RMSEA = 0.04, SRMR = 0.01). The analysis results suggested that depressive symptoms at T2 significantly mediated the longitudinal association between the two types of discrimination and the two types of couple relationships spanning 8 years while controlling for race, age, gender, education, number of reasons for everyday discrimination and T1 assessments of couple support and couple strain. However, allostatic load was not found to be a significant mediator between the two types of discrimination and the two aspects of couple relationship functioning (couple support and couple strain). The direct relationship between discrimination (everyday and major lifetime discrimination) and couple relationship functioning (couple strain and couple support) was not significant either. The results from the multi-group analysis suggested that several structural paths differed significantly across gender, age groups, and number of reasons for everyday discrimination, but none of the paths differed significantly based on race. Overall, the current study did not find evidence supporting the pathway from perceived discrimination to couple relationship functioning through allostatic load. It provided evidence supporting depressive symptoms as a mediating mechanism between perceived discrimination and couple relationship functioning. Future work should develop innovative methods for assessing and measuring allostatic load to test its possible mediation role between perceived discrimination and couple relationship functioning. Moreover, effective and culturally-responsive interventions and programs are needed to decrease all types of discrimination and depression in order to improve couple relationship functioning among middled-aged and older-aged adults in the U.S.Item Exposure to Ambient Air Pollution and Correlates of Cardiovascular Disease among Youth with Type 1 Diabetes(2019) Montresor-Lopez, Jessica Anne; Puett, Robin C; Maryland Institute for Applied Environmental Health; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)Air pollution from traffic-related sources is associated with cardiovascular disease (CVD), potentially through changes in systemic inflammatory responses, vascular function and oxidative stress leading to atherosclerosis, thrombosis or endothelial dysfunction. Individuals with type 1 diabetes (T1D) have a greater risk of CVD-related morbidity and mortality than the general population, and they may be more susceptible to the effects of air pollution on CVD. Although these increased risks begin during childhood, very few studies have assessed the impact of air pollution on children and youth with T1D. This dissertation directly addresses gaps in the epidemiologic evidence by: 1) evaluating the relationship of short-term exposures to traffic-related air pollutants with pulse wave velocity (PWV), a measure of arterial stiffness, 2) assessing the effects of changes in air pollution exposures on changes in inflammatory biomarkers, including C-reactive protein, fibrinogen and interleukin-6 (IL-6), and 3) examining the relationship of long-term exposures to traffic-related air pollution with allostatic load (AL), a measure of cumulative biological risk, among a cohort of youth with T1D. Data were obtained from the SEARCH for Diabetes in Youth (SEARCH) study. SEARCH was initiated in 2000 and includes a diverse population of US youth diagnosed with diabetes prior to age 20 years. Anthropometric and laboratory measures were taken at SEARCH study visits, and standardized questionnaires were used to collect information on important covariates. Air pollution exposures were estimated using spatio-temporal models and assigned to residential addresses for each participant. In the first study, we identified a significant association between increased exposure to PM2.5 on the day of the examination with higher PWV using generalized linear models adjusted for lifestyle and demographic characteristics. In the second analysis, we found consistent positive effects of increases in PM2.5 over the week prior to the examination with IL-6 using longitudinal mixed models. In the third study, no significant associations were observed for monthly and annual PM2.5 exposures or proximity to major roadways with AL in fully adjusted linear mixed models. However, effects differed by race/ethnicity and gender. Overall, this research indicates that youth with T1D may be at higher risk for air pollution-related cardiovascular impacts.