Theses and Dissertations from UMD

Permanent URI for this communityhttp://hdl.handle.net/1903/2

New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a give thesis/dissertation in DRUM

More information is available at Theses and Dissertations at University of Maryland Libraries.

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    A DATA ANALYTICAL FRAMEWORK FOR IMPROVING REAL-TIME, DECISION SUPPORT SYSTEMS IN HEALTHCARE
    (2010) Yahav, Inbal; Shmeuli, Galit; Business and Management: Decision & Information Technologies; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    In this dissertation we develop a framework that combines data mining, statistics and operations research methods for improving real-time decision support systems in healthcare. Our approach consists of three main concepts: data gathering and preprocessing, modeling, and deployment. We introduce the notion of offline and semi-offline modeling to differentiate between models that are based on known baseline behavior and those based on a baseline with missing information. We apply and illustrate the framework in the context of two important healthcare contexts: biosurveillance and kidney allocation. In the biosurveillance context, we address the problem of early detection of disease outbreaks. We discuss integer programming-based univariate monitoring and statistical and operations research-based multivariate monitoring approaches. We assess method performance on authentic biosurveillance data. In the kidney allocation context, we present a two-phase model that combines an integer programming-based learning phase and a data-analytical based real-time phase. We examine and evaluate our method on the current Organ Procurement and Transplantation Network (OPTN) waiting list. In both contexts, we show that our framework produces significant improvements over existing methods.