Theses and Dissertations from UMD

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New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a give thesis/dissertation in DRUM

More information is available at Theses and Dissertations at University of Maryland Libraries.

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    Immunopotency of a novel catanionic surfactant vesicle vaccine for bovine mastitis
    (2014) Vasudevan, Prarthana; Stein, Daniel C; Cell Biology & Molecular Genetics; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    17-20% of the world's cows have had bovine mastitis at some point in their lives. Mastitis is the inflammation of mammary glands caused by infection, such as by the bacterium Escherichia coli. The focus of this thesis research is the immunopotency of a novel catanionic surfactant vesicle vaccine for E. coli mastitis that could theoretically resemble an `artificial pathogen.' To this end, serum studies analyzing antibody titers and immunogenic profiles were conducted. These studies demonstrate that there was no significant increase in total E. coli specific-IgG in vaccinated cows post-vaccination and that there may be variation in immunogenic profiles post-vaccination.