Theses and Dissertations from UMD

Permanent URI for this communityhttp://hdl.handle.net/1903/2

New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a give thesis/dissertation in DRUM

More information is available at Theses and Dissertations at University of Maryland Libraries.

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Author: search.filters.author.Katsipis, IakovosSubject: search.filters.subject.decision making

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    Health Care Management System for Diabetes Mellitus: A Model-based Systems Engineering Framework
    (2015) Katsipis, Iakovos; Baras, John S.; Systems Engineering; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    The present thesis develops a framework for Health Care Management Systems using modern Model-Based Systems Engineering methodologies and applies it to Diabetes Mellitus. The desired architecture of such systems is described. Tests and interventions, including Health Care IT, used for Diabetes 2 diagnosis and treatment, are described and modeled. A Controlled Markov Chain model for the progression of Diabetes Mellitus with three states, three diagnostic tests, ten interventions, three patient types, is developed. Evaluation metrics for healthcare quality and associated costs are developed. Using these metrics and disease models, two methods for tradeoff analysis between healthcare quality and costs are developed and analyzed. One is an exhaustive Monte Carlo simulation and the other utilizes multi-criteria optimization with full state information. The latter obtains similar results as the former at a fraction of the time. Practical examples illustrate the powerful capabilities of the framework. Future research directions and extensions are described.