Theses and Dissertations from UMD

Permanent URI for this communityhttp://hdl.handle.net/1903/2

New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a give thesis/dissertation in DRUM

More information is available at Theses and Dissertations at University of Maryland Libraries.

Browse

Filters

20071

Settings

Author: search.filters.author.Charbonneau, DavidSubject: search.filters.subject.Health Sciences, General

Search Results

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Association Between ACE Genotype and Skeletal Muscle Strength and Volume, and Their Response to Strength Training in Older Adults
    (2007-06-29) Charbonneau, David; Roth, Stephen; Kinesiology; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    Introduction: Previous studies have linked an insertion/deletion polymorphism in the angiotensin-converting enzyme (ACE) gene with variability in the response of muscle strength and mass to strength training, though conclusions have been inconsistent across investigations. The purpose of this study was to investigate the possible association between ACE genotype and skeletal muscle strength and volume, and their adaptation to strength training. Methods: A group of older, sedentary adults completed 10-weeks of strength training. Quadriceps muscle strength and volume were measured using one repetition maximum and computed tomography, respectively. Differences were compared among ACE genotype groups (II vs. ID+DD) by sex and race. Results: Baseline and post-training, skeletal muscle strength and volume were not significantly correlated with ACE genotype. ACE genotype was significantly associated with muscle hypertrophy in Caucasian males only (p=0.02). Conclusions: The ACE genotype was not associated with skeletal muscle strength, but was associated with muscle hypertrophy in Caucasian males.