Ethnic and Racial Differences in the Smoking-Related Risk of Lung Cancer

Simple item page
dc.contributor.authorHaiman, Christopher A.
dc.contributor.authorStram, Daniel O.
dc.contributor.authorWilkens, Lynne R.
dc.contributor.authorPike, Malcolm C.
dc.contributor.authorKolonel, Laurence N.
dc.contributor.authorHenderson, Brian E.
dc.contributor.authorLe Marchand, Loïc
dc.date.accessioned2019-08-14T15:00:01Z
dc.date.available2019-08-14T15:00:01Z
dc.date.issued2006
dc.description.abstractBackground There is remarkable variation in the incidence of lung cancer among ethnic and racial groups in the United States. Methods We investigated differences in the risk of lung cancer associated with cigarette smoking among 183,813 African-American, Japanese-American, Latino, Native Hawaiian, and white men and women in the Multiethnic Cohort Study. Our analysis included 1979 cases of incident lung cancer identified prospectively over an eight-year period, between baseline (1993 through 1996) and 2001. Results The risk of lung cancer among ethnic and racial groups was modified by the number of cigarettes smoked per day. Among participants who smoked no more than 30 cigarettes per day, African Americans and Native Hawaiians had significantly greater risks of lung cancer than did the other groups. Among those who smoked no more than 10 and those who smoked 11 to 20 cigarettes per day, relative risks ranged from 0.21 to 0.39 (P<0.001) among Japanese Americans and Latinos and from 0.45 to 0.57 (P<0.001) among whites, as compared with African Americans. However, at levels exceeding 30 cigarettes per day, these differences were not significant. Differences in risk associated with smoking were observed among both men and women and for all histologic types of lung cancer. Conclusions Among cigarette smokers, African Americans and Native Hawaiians are more susceptible to lung cancer than whites, Japanese Americans, and Latinos.
dc.description.urihttps://www.nejm.org/doi/full/10.1056/NEJMoa033250
dc.identifierhttps://doi.org/10.13016/z6es-74x9
dc.identifier.citationHaiman, Christopher A. and Stram, Daniel O. and Wilkens, Lynne R. and Pike, Malcolm C. and Kolonel, Laurence N. and Henderson, Brian E. and Le Marchand, Loïc (2006) Ethnic and Racial Differences in the Smoking-Related Risk of Lung Cancer. The New England Journal of Medicine, 354 (4). pp. 333-342.
dc.identifier.otherEprint ID 663
dc.identifier.urihttp://hdl.handle.net/1903/22698
dc.subjectDisparities
dc.subjectCancer
dc.subjectSmoking & Tobacco Use
dc.subjectstudies
dc.subjectlung cancer
dc.subjectEthnic and Racial Differences
dc.subjectMultiethnic Cohort Study
dc.subjectrisk
dc.titleEthnic and Racial Differences in the Smoking-Related Risk of Lung Cancer
dc.typeArticle

Files

Collections

Minority Health and Health Equity Archive