This dissertation seeks to better understand how Mexican migrant women who work in the Maryland crab industry make sense of chronic illnesses such as diabetes, asthma, and musculoskeletal pain while at the same time living spatially and temporally complicated lives as circular temporary migrant laborers. I explore how immigration and labor policies and practices, constrained and conditional access to resources and care, and exposure to multiple forms of violence structure their chronic illness experiences and entanglements of biological and social processes that intersect. Together, these embodied biological and social processes coalesce into what I describe as problemas crónica-gendered “chronic problems” – and other disruptions that migrant women endure across time and transnational space. I describe how problemas crónicas manifest themselves throughout the lives and migratory careers of Mexican migrant women and how they grapple with obstacles as they seek care, renegotiate their identities, and re/build their lives.