Impact of Ethnicity on Primary Treatment Choice and Mortality in Men With Prostate Cancer: Data From CaPSURE

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dc.contributor.authorMoses, K. A.
dc.contributor.authorPaciorek, A. T.
dc.contributor.authorPenson, D. F.
dc.contributor.authorCarroll, P. R.
dc.contributor.authorMaster, V. A.
dc.date.accessioned2019-08-14T15:03:34Z
dc.date.available2019-08-14T15:03:34Z
dc.date.issued2010
dc.description.abstractPurpose Men diagnosed with prostate cancer have multiple options available for treatment. Previous reports have indicated a trend of differing modalities of treatment chosen by African American and white men. We investigated the role of ethnicity in primary treatment choice and how this affected overall and cancer-specific mortality. Methods By utilizing data abstracted from Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), patients were compared by ethnicity, primary treatment, number of comorbidities, risk level according to modified D'Amico criteria, age, highest educational level attained, type of insurance, treatment facility, and perception of general health. Multinomial logistic regression analysis was performed to determine the effect of the tested variables on primary treatment and mortality. Results African American men were more likely to receive nonsurgical therapy than white men with equivalent disease characteristics. Whites were 48% less likely than African Americans to receive androgen deprivation therapy (ADT) compared with surgery (P = .02) and were 25% less likely than African Americans to receive radiation therapy compared with surgery (P = .08). Whites with low-risk disease were 71% less likely to receive ADT than African American men with similar disease (P = .01). Adjusted overall and prostate cancer–specific mortality were not significantly different between whites and African Americans (hazard ratios, 0.73 and 0.37, respectively). Risk level, type of treatment, and type of insurance had the strongest effects on risk of mortality. Conclusion There is a statistically significant difference in primary treatment for prostate cancer between African American and white men with similar risk profiles. Additional research on the influence of patient/physician education and perception and the role that socioeconomic factors play in mortality from prostate cancer may be areas of focus for public health initiatives.
dc.description.urihttp://dx.doi.org/10.1200/JCO.2009.26.2469
dc.identifierhttps://doi.org/10.13016/ynzv-iqdc
dc.identifier.citationMoses, K. A. and Paciorek, A. T. and Penson, D. F. and Carroll, P. R. and Master, V. A. (2010) Impact of Ethnicity on Primary Treatment Choice and Mortality in Men With Prostate Cancer: Data From CaPSURE. Journal of Clinical Oncology, 28 (6). pp. 1069-1074.
dc.identifier.issn0732-183X
dc.identifier.otherEprint ID 2853
dc.identifier.urihttp://hdl.handle.net/1903/23493
dc.subjectHealth Equity
dc.subjectPublic Health
dc.subjectCancer
dc.subjectstudies
dc.subjectprostate cancer
dc.subjectethnicity
dc.subjectprimary treatment choice
dc.subjectcancer-specific mortality
dc.subjectsocioeconomic factors
dc.titleImpact of Ethnicity on Primary Treatment Choice and Mortality in Men With Prostate Cancer: Data From CaPSURE
dc.typeArticle

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