Examining Consumer Product Use And Phthalate Exposure Among Vulnerable Populations

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dc.contributor.advisorQuirós-Alcalá, Lesliamen_US
dc.contributor.authorBoyle, Meleahen_US
dc.contributor.departmentMaryland Institute for Applied Environmental Healthen_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.date.accessioned2023-06-23T05:41:01Z
dc.date.available2023-06-23T05:41:01Z
dc.date.issued2023en_US
dc.description.abstractOne in 13 Americans have asthma, and higher rates have been reported among women and Black children.1 In addition, hairdressers who are exposed to chemicals through products used on themselves and their clients frequently report respiratory symptoms and conditions.2–10 Limited studies indicate that chemicals in personal care and consumer products (PCP) may impact respiratory health.11–14 The goal of this dissertation is to describe PCP use and exposures to recognized and suspected respiratory irritants (phthalates) among vulnerable populations who may experience disparate exposures. The aims are to: 1) characterize PCP use among 110 children with asthma, 2) examine associations between PCP use and asthma morbidity among 110 children with asthma, and 3) characterize concentrations and exposure determinants to phthalate metabolites in post-shift urine samples among 23 female hairdressers and 17 female office workers. In aim 1, participants were majority Black (87%), males (56%), and aged 8-11 years (66%). Adolescents (12-17 years) and females reported more frequent use of hair, face, and body products compared to children (8-11 years) and males. Participants used chemical treatments on their hair as young as 4 years and females 11-16 years used feminine wipes, spray, and regular deodorant in the genital area. For aim 2, use of aerosol products, hair products, and nail polish were positively associated with maximal symptom days [number of aerosol products (aOR: 1.36; CI: 1.17, 1.59), hairspray (aOR: 1.63; CI: 1.14, 2.33), perfume (aOR: 1.40; CI: 1.11,1.77); shampoo (aOR: 1.34; CI: 1.05,1.73), hair sheen (aOR: 1.41; CI: 1.00, 2.00), nail polish (aOR: 2.42; CI: 1.72, 3.41)] among children with asthma. For Aim 3, the geometric mean (GM) for monoethyl phthalate (MEP) was 10 times higher among hairdressers (161.4 ng/mL) than office workers (15.3 ng/mL). Hairdressers who provided chemical services had higher GM MEP concentrations than those who did not: texturizing (200.2 vs. 115.4 ng/mL), relaxing (181.6 vs. 92.1 ng/mL), bleaching (182.3 vs. 71.6 ng/mL), hair color (171.9 vs. 83.2 ng/mL), and Brazilian blowout (181.4 vs. 134.6 ng/mL). Hairdressers who provided natural services had lower GM MEP concentrations than those who did not: twists (129.1 vs. 215.8 ng/mL), sister locs/locs (86.0 vs. 241.9 ng/mL), and afros (94.7 vs. 203.9 ng/mL). While larger studies are needed, this dissertation provides new data on PCP use and phthalate exposure among Black children and hairdressers.en_US
dc.identifierhttps://doi.org/10.13016/dspace/za62-d8j0
dc.identifier.urihttp://hdl.handle.net/1903/29928
dc.language.isoenen_US
dc.subject.pqcontrolledEnvironmental healthen_US
dc.subject.pquncontrolledAsthmaen_US
dc.subject.pquncontrolledChemical exposuresen_US
dc.subject.pquncontrolledDisparitiesen_US
dc.subject.pquncontrolledHairdressersen_US
dc.subject.pquncontrolledPersonal care productsen_US
dc.subject.pquncontrolledPhthalatesen_US
dc.titleExamining Consumer Product Use And Phthalate Exposure Among Vulnerable Populationsen_US
dc.typeDissertationen_US

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