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Fischell Department of Bioengineering
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UTILIZATION OF PNEUMATIC ARTIFICIAL MUSCLES TO STUDY EFFECTS OF LOAD HISTORY ON THE INTERVERTEBRAL DISC (2015)Degenerative disc disease is commonly linked with low back pain, a major musculoskeletal disorder contributing to an annual socioeconomic impact of over $100 billion. The intervertebral disc (IVD) plays a critical role in ...
Controlled Delivery of a Glutamate Receptor Modulator to Promote Regulatory T cells and Restrain Autoimmunity (2015)Autoimmunity occurs when the immune system incorrectly recognizes and attacks self-molecules. Current therapies involve broad immunosuppressants that are not curative and leave patients immunocompromised. Dendritic cells ...
(2015)It is well-established that proteins adopt specific three-dimensional structures. However, examples of proteins that can adopt more than one folded state have become increasingly more common. The objective of this thesis ...
(2015)Multifunctional nanoparticles represent a class of materials with diverse therapy and imaging properties that can be exploited for the treatment of cancers that have significantly progressed or advanced, which are associated ...
Investigation of Intercellular Adhesion Molecule-1 Targeted Drug Transport Across the Gastrointestinal Epithelium (2015)Contrary to systemic injection of therapeutics, oral formulations represent clear advantages to patients, healthcare systems, and pharmaceutical companies including safety, low cost and patient compliance. However, oral ...