Ma, LiSonstegard, Tad S.Cole, John B.VanTassell, Curtis P.Wiggans, George R.Crooker, Brian A.Tan, ChengPrakapenka, DzianisLiu, George E.Da, YangThe availability of a unique unselected Holstein line since 1964 provided a direct comparison between selected and unselected Holstein genomes whereas large Holstein samples provided unprecedented statistical power for identifying high-confidence SNP effects. Utilizing these unique resources, we aimed to identify genome changes affected by selection since 1964.en-USGenome landscapeGenetic selectionMilk productionFertilityImmunityGenome changes due to artificial selection in U.S. Holstein cattleArticle