Magidson, Jessica F.Joska, John A.Myers, BronwynBelus, Jennifer M.Regenauer, Kristen S.Andersen, Lena S.Majokweni, SybilO’Cleirigh, ConallSafren, Steven A.Substance use is prevalent in South Africa and associated with poor HIV treatment outcomes, yet, it is largely unaddressed in HIV care. Implementing an evidence-based, task-shared intervention for antiretroviral therapy (ART) adherence and substance use integrated into HIV care may be a feasible and effective way to improve HIV treatment outcomes and reduce substance use in this population.en-USRE-AIMHybrid designGlobal mental healthHIVSubstance useAntiretroviral therapy (ART) adherenceArticle