Clarke, JasonFuchs, JoelleForty-six million people aged 12 or older met the DSM-5 criteria this past year for substance use disorder (SUD). SUD, marked by the inability to control or cut down on substance use paired with clinical impairment, is linked to negative health and well-being across the life course. Individuals with mental illnesses face self-stigma, social stigma, and institutional stigma. Levels of stigma vary based on mental illness, with SUD being one of the most stigmatized disorders due to the belief that addiction is a personal choice. The overarching question for this project is, what is the association between individual health and mental health history and ratings of social stigma? We hypothesize that greater internalizing symptoms will be associated with greater social stigma towards substance use but less stigma towards general health. In addition, individuals with a disability will endorse greater social stigma towards substance use but less stigma towards general health. Data was sourced from the General Social Survey (GSS). Data included 3,544 participants (45.6% Male). Respondents were adults 18 or older in the United States who lived in noninstitutional housing at the time of interviewing. Chi-squared tests, One-way ANOVA with posthoc Tukey tests, and correlations were used to test the hypotheses. Only greater depressive and anxiety symptoms (but not disability) were associated with less social stigma towards general health. No psychopathology symptoms (i.e., anxiety or depressive symptoms) were associated with stigma towards substance use. The next step in this project is to examine whether other forms of mental illnesses are associated with social stigma toward SUD.en-USPsychology, BSOS, GARD Lab, Social stigma,Other