King, Patricia A.It has been sixty years since the beginning of the Tuskegee syphilis experiment and twenty years since its existence was disclosed to the American public. The social and ethical issues that the experiment poses for medicine, particularly for medicine's relationship with African Americans, are still not broadly understood, appreciated, or even remembered.[1] Yet a significant aspect of the Tuskegee experiment's legacy is that in a racist society that incorporates beliefs about the inherent inferiority of African Americans in contrast with the superior status of whites, any attention to the question of differences that may exist is likely to be pursued in a manner that burdens rather than benefits African Americans.BioethicsPublic HealthResearchTuskegee syphilis experimentAfrican Americansracist societyArticle